Mask Adherence and Rate of COVID-19 Across the United States

New state-by-state analysis shows a statistical association between high adherence to mask wearing and reduced rates of COVID-19 in the U.S. Charlie Fischer and colleagues at the Boston University School of Public Health in Massachusetts present these findings in the open-access journal PLOS ONE on April 14. Analysis showed that, out of 15 states that did not require people to wear […]

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Coronavirus conspiracy suspicions, general vaccine attitudes, trust, and coronavirus information source as predictors of vaccine hesitancy among UK residents during the COVID-19 pandemic

New research has found that the most reliable indicators of willingness to be vaccinated against SARS-CoV-2, the virus that causes COVID-19, are rejection of conspiracy suspicions about COVID-19 and a positive attitude towards vaccines in general. The study by King’s College London and the University of Bristol is published in the leading peer-reviewed journal Psychological Medicine. The researchers’ analysis was based […]

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Health Care Workers’ Reluctance to Take the Covid-19 Vaccine: A Consumer-Marketing Approach to Identifying and Overcoming Hesitancy

An anonymous survey of employees across the Yale Medicine and Yale New Haven Health system at the time of FDA approval of the Pfizer-BioNTech vaccine used sentiment analysis to estimate the prevalence of and underlying reasons for Covid-19 vaccine hesitancy. Overall, 1 in 6 health care workers expressed reluctance to getting the vaccine in the first wave. Yale identified 15 […]

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Characteristics and Clinical Outcomes of Adult Patients Hospitalized with COVID-19 – Georgia, March 2020

SARS-CoV-2, the novel coronavirus that causes coronavirus disease 2019 (COVID-19), was first detected in the United States during January 2020 (1). Since then, >980,000 cases have been reported in the United States, including >55,000 associated deaths as of April 28, 2020 (2). Detailed data on demographic characteristics, underlying medical conditions, and clinical outcomes for persons hospitalized with COVID-19 are needed […]

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Trends in Racial and Ethnic Disparities in COVID-19 Hospitalizations, by Region — United States, March–December 2020

Geographic and temporal differences were identified in racial and ethnic disparities in COVID-19 hospitalization levels during 2020, according to research published in the April 12 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. Sebastian D. Romano, M.P.H., from the CDC COVID-19 Response Team, and colleagues examined monthly trends in the proportion of hospitalized […]

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Time-dependent heterogeneity leads to transient suppression of the COVID-19 epidemic, not herd immunity

Scientists at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory and the University of Illinois Urbana-Champaign (UIUC) have developed a new mathematical model for predicting how COVID-19 spreads. This model not only accounts for individuals’ varying biological susceptibility to infection but also their levels of social activity, which naturally change over time. Using their model, the team showed that […]

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High-throughput, single-copy sequencing reveals SARS-CoV-2 spike variants coincident with mounting humoral immunity during acute COVID-19

Sung Hee Ko of the National Institute of Allergy and Infectious Diseases in Bethesda, Maryland, and colleagues developed new technology for genetic sequencing of the SARS-CoV-2 spike protein, enabling detection of multiple SARS-CoV-2 strains that may be present at the same time within a single infected patient. Previous studies have used standard sequencing methods to produce a single genetic sequence […]

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SARS-CoV-2 Infection of the Oral Cavity and Saliva

Researchers generated and analyzed two single-cell RNA sequencing datasets of the human minor salivary glands and gingiva (9 samples, 13,824 cells), identifying 50 cell clusters. Using integrated cell normalization and annotation, they classified 34 unique cell subpopulations between glands and gingiva. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral entry factors such as ACE2 and TMPRSS members were broadly enriched in epithelial […]

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illingness to Receive a COVID-19 Vaccination Among Incarcerated or Detained Persons in Correctional and Detention Facilities—Four States

Fewer than half of inmates in jails and prisons surveyed in a study by the CDC and University of Washington said they would accept a COVID-19 vaccine, while the majority either said they wanted to wait before getting the vaccine or would refuse one. “This is a population already at risk for COVID-19, and outbreaks among incarcerated people can worsen […]

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